There is no version of Desktop Manager that supports synching with Microsoft Works. Versions 4.3 and higher support the following PIMs:
Organizer Support
Lotus Notes� 6.0, 6.5, 7.0, 8.0
MS Outlook� 2002, 2003, 2007
MS Outlook Express 6, Windows Contacts (Vista Address Book)
Novell� GroupWise� 6.5, 7.0
Yahoo!� PIM